VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • Alaskan Husky

AHE-Alaskan Husky Encephalopathy

Alaskan Husky Encephalopathy (AHE) is a rare hereditary and rapidly fatal neurological disease affecting predominantly Alaskan Huskies and is caused by a mutation in the thiamine transporter 2 (SLC19A3) gene. The disease often affects multiple dogs from the same litter.

The disease is characterized by necrosis of the brain and clinical signs such as seizures,visual problems, trouble walking and difficulty eating, usually appear at 2 - 7 months of age. AHE is inherited as a simple autosomal recessive trait.

Result types: Clear, Carrier, Affected