VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • American Bulldog
  • Australian Shepherd
  • Bordeaux Mastiff
  • Bulldog
  • Bullmastiff
  • Cane Corso
  • English Bulldog
  • English Mastiff
  • French Bulldog
  • Great Pyrenees
  • Mastiff
  • CMR2
  • Coton de Tulear

Canine Multifocal Retinopathy (CMR1 & CMR2)

The tests for CMR1 and CMR2 offered by Vetgen are based on the work presented by Zangerl et al. at the fifth international symposium on "Advances in Canine and Feline Genomics and Inherited Disease." The research identified recessive mutations in the BEST1 gene that lead to CMR in puppies which inherit a mutant copy of the gene from each parent. Affected animals generally show their first symptoms in their first year.

While both mutations are in the same gene, they are breed specific and testing for only one is required. Coton de Tulear need only test for CMR2 which tests for a mutation only seen in that breed to date. All other breeds that are offered should test for CMR1.