VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • Labrador Retriever
  • Jack/Parson Russell Terrier
  • Parson/Jack Russell Terrier

CMSs-Congenital myasthenic syndromes

Congenital myasthenic syndromes (CMSs) form a heterogeneous group of very rare genetic diseases characterized by a dysfunction of neuromuscular transmission because of mutations in numerous genes. These neuromuscular disorders are characterized by skeletal muscle weakness and fatigue.

CMSs disorders occur usually in animals between 6 to 12 weeks of age and appear to be familial and inherited predominantly in an autosomal recessive manner.