- Great Pyrenees
Glanzmann's Thrombasthenia (GT) is a rare bleeding disorder in which the platelets are defective. Platelets have the ability to stick together to stop the flow of blood from injured blood vessels until clotting and tissue repair occurs. While dogs with GT have normal platelet counts, they have abnormal platelet aggregation and blood clotting and thus are at risk of life-threatening bleeding, including spontaneous hemorrhage and excessive hemorrhage as a result of injury or surgery. The disease often manifests itself in young dogs with bleeding gums and/or nosebleeds. GT has been recognized in several breeds, in particular Otter Hounds and Great Pyrenees.
GT is an inherited autosomal recessive disorder.