- Shih Tzu
Breeds Serviced
Prekallikrein deficiency, Fletcher factor deficiency
Prekallikrein deficiency, also known as Fletcher Trait, is rare inherited autosomal recessive bleeding disorder where the coagulation activation rate of factor XII is compromised by the absence of the KLKB1 plasma Kallikrein antibody. The condition is characterized by slow healing, abnormal post-surgical bleeding and sometimes excessive gastrointestinal bleeding or presence of blood in the urine.
