VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

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List of Services

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VetGen is continually doing research on many different diseases and genetic traits. Below is a list of services that VetGen currently offers.

Breed Identification Tests

Mixed Breed Dogs

Over 25 million mixed-breed dog owners know their dogs...but not as well as they could. With the simple swipe of a cheek swab, Wisdom Panel® Insights can determine the ancestry of a mixed-breed dog by testing for more than 185 breeds, the largest database on the market. Within three weeks, dog owners will be e-mailed an official Ancestry Report that reveals the dog's genetic background.
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Designer Dogs

Wisdom Panel® Designer Dog certification test kit provides Designer Dog owners with the peace of mind that they:

  1. Own a true Designer Dog with purebred parents.
  2. Possess the knowledge to care for their specific Designer Dog type.

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Purebred Dogs

Wisdom Panel® Purebred evaluates the genetic patterns within your dog compared with the genetic signatures observed in our database of known purebred dogs.
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Genetic Trait Tests

Color traits

For many years geneticists and breeders have been aware of several "loci" that are responsible for the color patterns we see in dogs and other mammals. Each of these loci are known to be responsible for one or more traits either independently, or in conjunction with another locus. more

Non-color traits

Coat Length

While it is not a color trait, the length of a dog's coat is of interest to many. more

Furnishings

Furnishings refer to the variation of longer facial hair seen in all wire haired breeds as well as some others. more

Curly

A mutation responsible for curly coat in dogs has recently been identified in the KRT71 gene.
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Genetic Disease Tests

BNAt

Vetgen’s test is based on the work presented by O’Brien et al at the 2010 Advances in Canine and Feline Genomics and Inherited Disease. more

CMR1 & CMR2

The tests for CMR1 and CMR2 offered by Vetgen are based on the work presented by Zangerl et al. at the fifth international symposium on "Advances in Canine and Feline Genomics and Inherited Disease. more

cord1 - PRA

Cone-Rod Dystrophy 1 - Progressive Retinal Atrophy (cord1 - PRA) is an inherited disease of the eye that affects the cone and rod cells that make up the dog's retina and often leading to blindness. more

CNM-Centronuclear Myopathy

Centronuclear myopathy in Labrador Retrievers is a recessively inherited muscular disease. This disease was previously known as Labrador muscular myopathy. more

CT-Copper Toxicosis

Canine copper toxicosis ("CT") is an autosomal recessive disorder of copper accumulation which results in severe liver disease in several dog breeds. Unless specific anti-copper treatment is instituted, most affected dogs die at three to seven years of age. CT is, in particular, a severe problem in Bedlington Terriers. more

Cyclic Neutropenia

Canine Cyclic Neutropenia Canine cyclic neutropenia, also known as gray collie syndrome (GCS), is an autosomal recessive disease. Both parents must carry the abnormal gene for the offspring to be affected. more

Cystinuria

Cystinuria in the Newfoundland dog is indicated by the presence of cystine stones in the kidney, bladder or ureter. Failure by the kidneys to reabsorb amino acids results in the formation of these stones. more

Dilated Cardiomyopathy

This disease of the heart can result in sudden death of relatively young dogs. more

Factor VII Deficiency

Factor VII deficiency is a generally mild bleeding disorder. more

Factor XI Deficiency

Factor XI deficiency is a clotting (coagulation) factor deficiencies that affects Kerry Blue Terriers.

Greyhound Polyneuropathy

Greyhound Polyneuropathy is a severe and progressive disease which is found in show lines of the Greyhound breed. more

Hemophilia B

Hemophilia B is often a severe bleeding disorder caused by a deficiency of coagulation factor IX resulting in a severely affected blood clotting process. more

Hereditary Cataract

There are several types of inherited cataract in the dog which vary in both their appearance and age of onset. The majority of these are inherited as autosomal recessive traits, but some are inherited as dominant or perhaps polygenic trait. more

Hyperuricosuria

Inherited hyperuricosuria causes dogs to produce urine with very high levels of uric acid. This can lead to bladder stones, and less frequently kidney stones. more

Hereditary Nephritis

Hereditary nephritis in the Samoyed is a dominant, X-linked disease that affects young male dogs more severely than females. more

NCL-Neuronal Ceroid Lipofuscinosis

A young-adult onset NCL occurs in American Bulldogs and a mutation in the cathepsin D gene (CSTD) responsible for NCL in this breed has been identified. (Awano et al 2006) more

NE-Neonatal Encephalopathy

Neonatal encephalopathy is a recessive developmental brain disease. more

PDP1

Pyruvate Dehydrogenase Phosphatase 1 deficiency is characterized by exercise intolerance and post-exercised collapse. more

PFK-Phosphofructokinase deficiency

Canine Phosphofructokinase (PFK) deficiency is an autosomal recessive genetic disease which prevents the metabolism of glucose into available energy resulting in exercise intolerance and muscle disease in Cocker Spaniels. more

PK-Pyruvate Kinase deficiency

Pyruvate kinase (PK) deficiency in Basenji dogs is an inherited lack of an enzyme (pyruvate kinase) in the red blood cells of an affected animal. more

PRA-Progressive Retinal Atrophy

Irish setter progressive retinal atrophy (PRA) is an inherited disease that leads to blindness in affected dogs. It is inherited in a simple autosomal recessive fashion. more

PLL-Primary Lens Luxation

PLL is an inherited condition that affects many breeds of dog. It is characterized my movement of the lens away from its normal location in the eye. more

RCND

Renal Cystadenocarcinoma Nodular Dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. more

vWD

von Willebrand’s disease has been identified in a wide range of canine breeds, and is the most common of the inherited bleeding disorders. As with humans, there are three classifications of this disease, Types I, II, and III.  These are based on the concentration and nature of plasma vWF. more

Type I vWD

VetGen scientists, in collaboration with the University of Michigan and Michigan State University, proudly announce the discovery of the mutation that causes Type I von Willebrand's Disease (vWD) and the offering of a DNA test to detect vWD in the above breeds. more

Type II vWD

Type II vWD is characterized by abnormal vWF, as opposed to low levels of normal vWF. This type is not as common as Type I, but a mutation causing it has been identified in some pointing breeds and Deutch Drahthaar. more

Type III vWD

Canine von Willebrand's disease (vWD) in Scotties is an autosomal recessive genetic disease with a gene frequency estimated to be 15% of the Scottie population. more

Other Genetic Services

Profiling/Parentage/Storage

In addition to offering genetic testing services for the detection of color genes and of targeted canine diseases, VetGen offers other valuable services. These services, DNA Profiling, DNA Parentage and DNA Storage, can be ordered at the time a genetic test is requested, or at any other time, independent of other tests.
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Other Services

OFA Registration of Disease Test Results

OFA Registry The OFA, Orthopedic Foundation for Animals, has created a voluntary registry for the results of all VetGen Direct and Linked Marker DNA disease tests. We encourage you to register your dog's test findings with the OFA. more

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