List of ServicesSampling is easy: Oral Cheek Swab!
VetGen is continually doing research on many different diseases and genetic traits. Below is a list of services that VetGen currently offers.
Breed Identification Tests
Mixed Breed Dogs
Over 25 million mixed-breed dog owners know their dogs...but not as well as they could. With the simple swipe of a cheek swab, Wisdom Panel® Insights can determine the ancestry of a mixed-breed dog by testing for more than 185 breeds, the largest database on the market. Within three weeks, dog owners will be e-mailed an official Ancestry Report that reveals the dog's genetic background.
Wisdom Panel® Designer Dog certification test kit provides Designer Dog owners with the peace of mind that they:
- Own a true Designer Dog with purebred parents.
- Possess the knowledge to care for their specific Designer Dog type.
Wisdom Panel® Purebred evaluates the genetic patterns within your dog compared with the genetic signatures observed in our database of known purebred dogs.
Genetic Trait Tests
For many years geneticists and breeders have been aware of several "loci" that are responsible for the color patterns we see in dogs and other mammals. Each of these loci are known to be responsible for one or more traits either independently, or in conjunction with another locus. more
Coat LengthWhile it is not a color trait, the length of a dog's coat is of interest to many. more
FurnishingsFurnishings refer to the variation of longer facial hair seen in all wire haired breeds as well as some others. more
CurlyA mutation responsible for curly coat in dogs has recently been identified in the KRT71 gene.
Genetic Disease Tests
Albinism in Doberman Pinscher more
Vetgen’s test is based on the work presented by O’Brien et al at the 2010 Advances in Canine and Feline Genomics and Inherited Disease. more
The tests for CMR1 and CMR2 offered by Vetgen are based on the work presented by Zangerl et al. at the fifth international symposium on "Advances in Canine and Feline Genomics and Inherited Disease. more
Cone-Rod Dystrophy 1 - Progressive Retinal Atrophy (cord1 - PRA) is an inherited disease of the eye that affects the cone and rod cells that make up the dog's retina and often leading to blindness. more
Centronuclear myopathy in Labrador Retrievers is a recessively inherited muscular disease. This disease was previously known as Labrador muscular myopathy. more
Canine copper toxicosis ("CT") is an autosomal recessive disorder of copper accumulation which results in severe liver disease in several dog breeds. Unless specific anti-copper treatment is instituted, most affected dogs die at three to seven years of age. CT is, in particular, a severe problem in Bedlington Terriers. more
Canine Cyclic Neutropenia Canine cyclic neutropenia, also known as gray collie syndrome (GCS), is an autosomal recessive disease. Both parents must carry the abnormal gene for the offspring to be affected. more
Cystinuria in the Newfoundland dog is indicated by the presence of cystine stones in the kidney, bladder or ureter. Failure by the kidneys to reabsorb amino acids results in the formation of these stones. more
This disease of the heart can result in sudden death of relatively young dogs. more
Factor VII deficiency is a generally mild bleeding disorder. more
Factor XI Deficiency
Factor XI deficiency is a clotting (coagulation) factor deficiencies that affects Kerry Blue Terriers.
Greyhound Polyneuropathy is a severe and progressive disease which is found in show lines of the Greyhound breed. more
Hemophilia B is often a severe bleeding disorder caused by a deficiency of coagulation factor IX resulting in a severely affected blood clotting process. more
There are several types of inherited cataract in the dog which vary in both their appearance and age of onset. The majority of these are inherited as autosomal recessive traits, but some are inherited as dominant or perhaps polygenic trait. more
Inherited hyperuricosuria causes dogs to produce urine with very high levels of uric acid. This can lead to bladder stones, and less frequently kidney stones. more
Hereditary nephritis in the Samoyed is a dominant, X-linked disease that affects young male dogs more severely than females. more
Neonatal encephalopathy is a recessive developmental brain disease. more
Pyruvate Dehydrogenase Phosphatase 1 deficiency is characterized by exercise intolerance and post-exercised collapse. more
Canine Phosphofructokinase (PFK) deficiency is an autosomal recessive genetic disease which prevents the metabolism of glucose into available energy resulting in exercise intolerance and muscle disease in Cocker Spaniels. more
Pyruvate kinase (PK) deficiency in Basenji dogs is an inherited lack of an enzyme (pyruvate kinase) in the red blood cells of an affected animal. more
Irish setter progressive retinal atrophy (PRA) is an inherited disease that leads to blindness in affected dogs. It is inherited in a simple autosomal recessive fashion. more
PLL is an inherited condition that affects many breeds of dog. It is characterized my movement of the lens away from its normal location in the eye. more
Renal Cystadenocarcinoma Nodular Dermatofibrosis (RCND) is a naturally occurring canine kidney cancer syndrome that was originally described in German Shepherd dogs. more
von Willebrand’s disease has been identified in a wide range of canine breeds, and is the most common of the inherited bleeding disorders. As with humans, there are three classifications of this disease, Types I, II, and III. These are based on the concentration and nature of plasma vWF. moreType I vWD
VetGen scientists, in collaboration with the University of Michigan and Michigan State University, proudly announce the discovery of the mutation that causes Type I von Willebrand's Disease (vWD) and the offering of a DNA test to detect vWD in the above breeds. moreType II vWD
Type II vWD is characterized by abnormal vWF, as opposed to low levels of normal vWF. This type is not as common as Type I, but a mutation causing it has been identified in some pointing breeds and Deutch Drahthaar. moreType III vWD
Canine von Willebrand's disease (vWD) in Scotties is an autosomal recessive genetic disease with a gene frequency estimated to be 15% of the Scottie population. more
Other Genetic Services
In addition to offering genetic testing services for the detection of color genes and of targeted canine diseases, VetGen offers other valuable services. These services, DNA Profiling, DNA Parentage and DNA Storage, can be ordered at the time a genetic test is requested, or at any other time, independent of other tests.
OFA Registry The OFA, Orthopedic Foundation for Animals, has created a voluntary registry for the results of all VetGen Direct and Linked Marker DNA disease tests. We encourage you to register your dog's test findings with the OFA. more