VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • Persian
  • Exotic
  • Himalyan


VetGen Laboratory is now proudly offering the new DNA test for Polycystic Kidney Disease (PKD) in Persian and all Persian related cats.

PKD is a inherited Kidney disease and most prevalent in cats. It is believed that within the cat population throughout the world this disease is affecting about six percent of cats. PKD is an abnormality particularly prevalent in Persian cats with an estimated frequency of 37%, this accounting for almost 80% of the cat population.

Because of the fact that the disease is a dominant, only one copy of the mutated gene (in one parent) is required to pass on the disease to it's progeny.

The disease is a autosomal dominant with variable onset, this meaning, a cat unless she dies of other causes prior to onset of PKD, will at some stage of it's life become ill from the disease, but onset time can not be determined because of it's variability.

The value of the new DNA test is that now you, the breeder and fancier, can test prospective adult cats before mating and kittens at a very early stage of their life, instead of having to wait the 9 months period for an ultrasound. The DNA test is definitive and 100% accurate in determining animals who have One Mutated Gene, this finding is NOT possible via the clinical methods of testing and therefore better breeding decisions can be made.

We use cheek swabs (sterile buccal swabs, which are used across the world in human and animal genetics) as a method of testing, they are non evasive to the animal and samples do not deteriorate in transit and actually can be stored over long periods of time.

The availability of the DNA test now can prevent much hardship, as testing can be done as soon as the little cheek swabs (tiny brushes resembling that of a soft bottle brush), can be inserted into the mouth of the kitten. These cheek swabs collect tissue which contains the DNA which is later extracted in the lab.

The DNA test results are defined as follows:

  1. Does not carry the mutation - will not produce the mutation if both parents have this test result status
  2. Carries one copy of the mutation - can pass on the mutation even if mated to a breeding partner who has No Mutated Gene
  3. Carries two copies of the mutation - this finding would, if at all possible, be very rare as these cats are known to die in uterus

The procedure of ordering the DNA test for PKD is, that you contact VetGen via email or phone with your postal details as well as payment details. You can also print out the order form from the web page, fill it in and send by normal mail (with payment or payment details as all tests are prepaid).

Payment can be made via credit card (Visa or MC) and expiry date, or by personal check.

After VetGen receives your order, you will receive your testing kit, which will include a form to fill in all your and your cats details, as well as a instruction sheet for sample collection.

You will receive a result certificate once test results become available. Results are strictly confidential and are only given to the person nominated on the order form.

However, it is in the breeds and breeders best interest to share as much information as possible to reduce if not eliminate this disease from the breeding stock.