Breeding Strategies
VetGen's DNA test findings can be extremely valuable when developing and implementing your breeding plans.
Interpreting your DNA test results for autosomal dominant diseases
There are only two possible test results for autosomal dominant diseases, affected or clear.
Clear
This finding means that no copies of the disease causing mutation are present and the animal will not be affected by the disease and is safe to use in a breeding program.
AFFECTED
This finding indicates that either one or two copies of the disease causing mutation are present. While the animal may or may not be exhibiting signs of the disease, it should not be used in any breeding program.
The only acceptable BREEDING STRATEGY for an autosomal dominant disease is CLEAR to CLEAR.
Helpful Feline Breeding Chart
| Clear Male | Affected Male (1 copy) |
Affected Male 1 copies) |
|
| Clear Female | 100% Clear | 50%clear/50% affected | 100% affected |
| Affected Female (1 copy) |
50%clear/50% affected | 25% clear/75% affected | 100% affected |
| Affected Female (2 copies) |
100% affected | 100% Affected | 100% affected |
Ideal Breeding Pair - Kittens will not have the disease gene.
High Risk Breeding - 50% affected and 50% clear
Breeding Not Recommended - All kittens will be genetically and medically affected

