VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeding Strategies


VetGen's DNA test findings can be extremely valuable when developing and implementing your breeding plans.

Interpreting your DNA test results for autosomal dominant diseases


There are only two possible test results for autosomal dominant diseases, affected or clear.

Clear
This finding means that no copies of the disease causing mutation are present and the animal will not be affected by the disease and is safe to use in a breeding program.

AFFECTED
This finding indicates that either one or two copies of the disease causing mutation are present. While the animal may or may not be exhibiting signs of the disease, it should not be used in any breeding program.

The only acceptable BREEDING STRATEGY for an autosomal dominant disease is CLEAR to CLEAR.

Helpful Feline Breeding Chart


Clear Male Affected Male
(1 copy)
Affected Male
1 copies)
Clear Female 100% Clear 50%clear/50% affected 100% affected
Affected Female
(1 copy)
50%clear/50% affected 25% clear/75% affected 100% affected
Affected Female
(2 copies)
100% affected 100% Affected 100% affected


Ideal Breeding Pair - Kittens will not have the disease gene.

High Risk Breeding - 50% affected and 50% clear

Breeding Not Recommended - All kittens will be genetically and medically affected