VetGen - The leader in veterinary genetic disease research and genetic disease detection services for purebred animals

Breeds Serviced

  • Cavalier King Charles Spaniel

EFS-Episodic Falling Syndrome

Episodic falling syndrome (EFS) in the Cavalier King Charles Spaniel is an autosomal recessively inherited disease. EFS is characterized by short, hypertonic episodes in which the limbs of the animal stiffen, often to the point of immobilization. These episodes generally start to occur early in life and can be induced by multiple triggers although exercise and excitement seem to be the most frequent causes.

A Recently, two research groups independently identified the mutation responsible for this disease. The test Vetgen offers is based on the findings of these two groups.